'Mr SHERRINGTON exhibited a rabbit, in which he had placed a ligature round the optic nerve of the right side nine weeks previously. The operation had been performed witth antiseptic precautions, and the ligature used was of catgut, about a millimeter thick. This ligature was tied as tightly as possible.

On the evening of the day of operation the retinal vessels as conmpared with those of the healthy side were reduced to very fine streaks, perhaps a tenth of their previous diameter; no pulsation could be produced in them by compression, although that was easily done for the other eye.

The tension of the eyeball instead of being increased, as stated for rabbits by Prof. Stilling, was about -1.

Observation of the fundus was impossible for the next fortnight, because of opacity of the media, but duiring the whole of that period the tension on the ligatured side was never so great as on the healthy side.

At the present time, as was demonstrated, the tension was still lower than in the healthy eyeball. Moreover the retinal circulation has become reestablished, although the vessels, especially the arteries, are smaller than in the opposite side.

Pulsation becomes evident in these vessels on pressure being applied to the eyeball, just as on the uninjuired fundus of the left side.

The right eye is however completely blind. The iris does not react to light. Otherwise the eye to cursory examination would appear normal. Closer observation detects merely a slight nebula, the remnant of a keratitis that occurred in the first fortnight following the operation; and the refraction has become myopic, and astigmatic, being - 2 D as measured on the vertical vessels of the disc, and - 3.5 D as measured on the horizontal.

At the optic disc itself papillitis is passing, into atrophy.'