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Creator (Definite): William StirlingDate: 1878
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Cites Plate II, Journal of Physiology 1 (1) (1878). Figs. 1-3 from J.N. Langley, 'Some Remarks on the Formation of Ferment' and fig. 4 from W. Stirling, 'On Hyperplasia of the Muscular Tissue'.
Description:Explanation of figs. 1-3:
'PL. II. Figs. 1 and 2. From lung of cat affected with Ollulanus. a, air-vesicles; b, trabecule between air-vesicles; c, nuclei of epithelial cells of vesicles slightly out of focus. Dammar, purpurine, Hartnack Obj. V. oc. 3. Fig. 3. a, air-vesicle; b, trabecula splitting up at f into muscular fibres; c, swollen-up epithelial cells. Glycerine, logwood, Hartnack Obj. VII. oc. 3.' (67)
Figs 1-3 in text:
'In the lungs of the cat... embryos of Ollulanus occur in enormous numbers, and give rise to lobular pneumonia, and in sections of a lung so affected, the hypertrophy of the tissue between the air-vesicles is very marked. This inter-alveolar hypertrophy is largely due to a great increase in the number of the non-striped muscular fibres.
Figs. 1 and 2, Pl. II., show these changes: a, a are placed within air-vesicles which are seen to be surrounded with a dense network of fibres, containing many fusiform nuclei. The thick trabeculae (b) with their nuclei consist of longitudinally arranged bundles of muscular fibres, which cross each other here and there. At b, in Fig. 2, some of these fibres are seen to dip into the septum between two air-vesicles. I have succeeded in splitting uip these trabeculae and in isolating the muscular fibre-cells. Fig. 3 shows one of these trabeculae b, splitting up at c, and resolving itself into muscular fibre-cells at f. In Figs. 1 and 2, c represents the nuclei of the epithelial cells of air-vesicles slightly out of focus.' (66-67)
Fig. 3 in text:
'To obtain the isolated fibre-cells, I find that prolonged maceration of the chromic acid lung in a twenty per cent. solution of nitric acid answers admirably, and Fig. 3 was made in that way. In Fig. 3 the epithelial cells c are swollen up and altered, and present the appearance of those in desquamative pneumonia.' (67)