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Creators (Definite): F. Huth; John Newport LangleyDate: 1878
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Cited by J.N. Langley, 'On the Changes in Serous Glands during Secretion', Journal of Physiology 2 (4) (1879), pp. 261-322.
Description:'Nussbaum [note: 'Arch. f. Mik. Anat., Bd. XVI. s. 543, 1879.'] suggests that the transition-cells which I describe are different from the darkly-stained cells described by him; a comparison of the figure 1 of his first communication with mine [note: 'Op. cit.'], and of the figure 1 of his second communication [note: 'Arch. f. Mik. Anat., Bd. XV. s. 119, 1878.'] with my fig. 2, Plate VIII., adjoined to this Paper will, I think, shew that we are dealing with the same cells.' (272-273)
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Cited by J.N. Langley, 'Some Remarks on the Formation of Ferment in the Sub-maxillary Gland of the Rabbit', Journal of Physiology 1 (1) (1878), pp. 68-71.
Description:Fig. 4 in text:
'It appears to me, on the contrary [to the assertion of Nussbaum], that the cells composing the ductule [of the sub-maxillary gland of the Rabbit] are but slightly elongated or not at all, and graduate as regards size and appearance into the alveolar cells, so that of particular ones it is difficult to say whether they belong to the ductule, or to the alveolus; hence I name them transition cells. A favourable example of this transition is drawn in Pl. II., Fig. 4. This is taken from the sub-maxillary gland of a rabbit which had been treated with osmic acid, 1 per cent., for two hours; (a) ductule, (b) transition-cells, (c) alveolar cells proper. This offers an approximate explanation of the colouration by osmic acid of the transition-cells observed by Nussbaum, viz., that they are as much allied to the duct-cells as to the alveolar cells, and preserve the property of the duct-cells to readily reduce osmic acid.' (69)
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Cited by W. Stirling, 'On Hyperplasia of the Muscular Tissue of the Lungs', Journal of Physiology 1 (1) (1878), pp. 66-108.
Description:Explanation of figs. 1-3:
'PL. II. Figs. 1 and 2. From lung of cat affected with Ollulanus. a, air-vesicles; b, trabecule between air-vesicles; c, nuclei of epithelial cells of vesicles slightly out of focus. Dammar, purpurine, Hartnack Obj. V. oc. 3. Fig. 3. a, air-vesicle; b, trabecula splitting up at f into muscular fibres; c, swollen-up epithelial cells. Glycerine, logwood, Hartnack Obj. VII. oc. 3.' (67)
Figs 1-3 in text:
'In the lungs of the cat... embryos of Ollulanus occur in enormous numbers, and give rise to lobular pneumonia, and in sections of a lung so affected, the hypertrophy of the tissue between the air-vesicles is very marked. This inter-alveolar hypertrophy is largely due to a great increase in the number of the non-striped muscular fibres.
Figs. 1 and 2, Pl. II., show these changes: a, a are placed within air-vesicles which are seen to be surrounded with a dense network of fibres, containing many fusiform nuclei. The thick trabeculae (b) with their nuclei consist of longitudinally arranged bundles of muscular fibres, which cross each other here and there. At b, in Fig. 2, some of these fibres are seen to dip into the septum between two air-vesicles. I have succeeded in splitting uip these trabeculae and in isolating the muscular fibre-cells. Fig. 3 shows one of these trabeculae b, splitting up at c, and resolving itself into muscular fibre-cells at f. In Figs. 1 and 2, c represents the nuclei of the epithelial cells of air-vesicles slightly out of focus.' (66-67)
Fig. 3 in text:
'To obtain the isolated fibre-cells, I find that prolonged maceration of the chromic acid lung in a twenty per cent. solution of nitric acid answers admirably, and Fig. 3 was made in that way. In Fig. 3 the epithelial cells c are swollen up and altered, and present the appearance of those in desquamative pneumonia.' (67)