'Fig. 3. First detected appearance of moniliform change in apical dendron of dog's pyramidal cell after four hours' etherisation. Fig. 4. Moniliform swellings in dog's pyramidal cell after six hours' etherisation.' (37)


Fig. 3 in text:

'Dog 4. Ether for four hours.

(a) Cerebrum. The large pyramidal cells are decidedly rarefied (Plate 1, fig. 6). The main apical processes are usually denuded of Nissl's bodies; the basal dendrons occasionally show the same change. The edges of such cells are ragged. A few skeleton cells are seen. The glia cells are more swollen, but show no augmentation. By Cox's method the extreme tips of the apical processes are moniliform, but the swellings are small (fig. 3 in text). The basal dendrons are still normal.' (36)


Fig. 4 in text:

'Dog 5. Ether for six hours.

The condition seen is simply an exaggeration of that in the previous case. The change in the cortical cells has not advanced beyond 'rarefaction' but the glia cells are more numerous and cluster about the markedly affected cells. The next figure in the text (fig. 4) shows the increase in moniliform change. The cells of cerebellum and spinal cord have about the same condition as in the four hour case.' (37)