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Creator (Definite): W.L. TempletonDate: 26 May 1923
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Created by W.L. Templeton
26 May 1923
Description:‘A short account of the treatment of general paralysis of the insane by infection with malaria was given by Dr. E.W. Scripture at a meeting of the Medico-Psychological Association on November 23rd, as reported in the British Medical Journal of December 9th, 1922 (p. 1121). The principle depends on the fact that remissions in chronic disease may occur after an attack of an acute specific fever...
...[895-896]...
In this country and in some others the difficulty consists in obtaining suitable cases of benign malaria for purposes of inoculation. Once a single case has been inoculated there is then no difficulty in transferring the infection to other paralytics, and though this involves the transference of syphilitic blood, yet, in cases which have been thoroughly examined and found positive for syphilis, this is of little consequence. The method of continuous transference has been practised in Vienna, where two strains of plasmodia are being used-one after having been passed through 58 hosts, and the other through 38, in both cases without any reduction in the virulence of the infection. Attempts are being made to keep the parasite alive outside the body; so far it has not survived for more than eight hours.’ (895-896)
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Cites ‘Reports of Societies: General Paralysis,’ British Medical Journal 2(3232) (9th Dec. 1922).
Description:‘A short account of the treatment of general paralysis of the insane by infection with malaria was given by Dr. E.W. Scripture at a meeting of the Medico-Psychological Association on November 23rd, as reported in the British Medical Journal of December 9th, 1922 (p. 1121). The principle depends on the fact that remissions in chronic disease may occur after an attack of an acute specific fever...
...[895-896]...
In this country and in some others the difficulty consists in obtaining suitable cases of benign malaria for purposes of inoculation. Once a single case has been inoculated there is then no difficulty in transferring the infection to other paralytics, and though this involves the transference of syphilitic blood, yet, in cases which have been thoroughly examined and found positive for syphilis, this is of little consequence. The method of continuous transference has been practised in Vienna, where two strains of plasmodia are being used-one after having been passed through 58 hosts, and the other through 38, in both cases without any reduction in the virulence of the infection. Attempts are being made to keep the parasite alive outside the body; so far it has not survived for more than eight hours.’ (895-896)