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Sent From (Definite): Karl PearsonSent To (Definite): Edward NettleshipDate: 3 Sep 1911
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Holder (Definite): University College London: Special Collections
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Sent from Karl Pearson
3 Sep 1911
Description:
‘Dear Nettleship,
I have a note from Dr Coats this morning saying that he has identified the slide. Perhaps you have also heard & will let me know about reproduction. It is much less expensive to do a number of these sections on one plate & if this is desirable to combine it with Tong’s section & the Negro’s eye sections.
There is one point which very considerably disturbs me, and I think we may be playing at cross purposes with regard to hair pigment. Coats’ report on this albino puppy runs in part:
“Skin. Some of the larger hairs show some pigment in medulla and a few small areas[?] in cortex. No pigmentation in other epidermal structures; nor in cutis.”
Now intercellular pigment can be found very frequently in the hairs of clinically complete albinos. See Scott’s Report of which I enclose a copy, in case you have not got one. The real point is whether distinct pigment granules have been found. The simple statement that there is “pigment” [indicates?] something coloured – it may be a lipochrome & not a melanin at all – in the hair of an albino does not seem to me of importance – at any rate it ought to be of value to be accompanied by a distinct statement of whether it is granular or not. I wish you would read Scott through again – the Papuan albno (see p. 12) that I have underlined is a very typical [example] of what one finds. See also what I have underlined on p. 8 about De Creswell’s[?] hair. There is I know some difficulty in determining when there is intercellular pigment, whether granules really exist or not & we have often got two or three independent opinions, but I think it is very importnat to preserve the distinction between intercellular & granular pigment for the former appears in nearly 60% of albino hairs, if not more & the latter practically never in complete albinos.
Yours very sincerely,
Karl Pearson.
“Died young” means up to about 15, i.e. before adult stage, “died in infancy” in first two years of life. The distinction is not often certain on the records, but more frequently the characters are known of the “died young” than of the “died in infancy” which sometimes means in the first two or three weeks.’
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Sent to Edward Nettleship
3 Sep 1911
Description:
‘Dear Nettleship,
I have a note from Dr Coats this morning saying that he has identified the slide. Perhaps you have also heard & will let me know about reproduction. It is much less expensive to do a number of these sections on one plate & if this is desirable to combine it with Tong’s section & the Negro’s eye sections.
There is one point which very considerably disturbs me, and I think we may be playing at cross purposes with regard to hair pigment. Coats’ report on this albino puppy runs in part:
“Skin. Some of the larger hairs show some pigment in medulla and a few small areas[?] in cortex. No pigmentation in other epidermal structures; nor in cutis.”
Now intercellular pigment can be found very frequently in the hairs of clinically complete albinos. See Scott’s Report of which I enclose a copy, in case you have not got one. The real point is whether distinct pigment granules have been found. The simple statement that there is “pigment” [indicates?] something coloured – it may be a lipochrome & not a melanin at all – in the hair of an albino does not seem to me of importance – at any rate it ought to be of value to be accompanied by a distinct statement of whether it is granular or not. I wish you would read Scott through again – the Papuan albno (see p. 12) that I have underlined is a very typical [example] of what one finds. See also what I have underlined on p. 8 about De Creswell’s[?] hair. There is I know some difficulty in determining when there is intercellular pigment, whether granules really exist or not & we have often got two or three independent opinions, but I think it is very importnat to preserve the distinction between intercellular & granular pigment for the former appears in nearly 60% of albino hairs, if not more & the latter practically never in complete albinos.
Yours very sincerely,
Karl Pearson.
“Died young” means up to about 15, i.e. before adult stage, “died in infancy” in first two years of life. The distinction is not often certain on the records, but more frequently the characters are known of the “died young” than of the “died in infancy” which sometimes means in the first two or three weeks.’