'During the thirteen years that have elapsed since I invented the freezing microtome, the method of freezing has come into general use as an aid to microscopical research in physiology and pathology. It has also become of much service in aiding the practical study of these subjects, especially when they have to be taught to large numbers of students. The original ice and salt freezing microtome described by me in the Journal of Anatomy and Physiology for 1871, vol. v., was somewhat faulty. The improved form of the instrument (Fig. 2) described by me in The Lancet, 1873, vol. ii., has been constantly used in my laboratory since that time. We have no difficulty in making with it from four to five hundred sections of the retina, kidney, or other organ, in the course of an hour.' (4)

'During the thirteen years that have elapsed since I invented the freezing microtome, the method of freezing has come into general use as an aid to microscopical research in physiology and pathology. It has also become of much service in aiding the practical study of these subjects, especially when they have to be taught to large numbers of students. The original ice and salt freezing microtome described by me in the Journal of Anatomy and Physiology for 1871, vol. v., was somewhat faulty. The improved form of the instrument (Fig. 2) described by me in The Lancet, 1873, vol. ii., has been constantly used in my laboratory since that time. We have no difficulty in making with it from four to five hundred sections of the retina, kidney, or other organ, in the course of an hour.' (4)