'When I described in the pages of this Journal for May, 1871 (324), a method by which tissues might readily be frozen and cut for microscopical purposes by a modification of Stirling's microtome devised by me, I was aware that I bad rendered the freezing process available to the histologist in a way which would certainly prove of great service. And I was also aware that the freezing method would in the end largely supersede all other methods of imbedding the tissues for the purpose of making microscopical sections. I stated that, with the aid of my freezing apparatus (p. 326), "beautiful sections of frozen fresh lung, liver, kidney, muscle, skin, brain, etc., may be made with an ordinary razor," and moreover that the capabilities of my apparatus might be readily appreciated from the following experiment (p. 328): 'I killed a rabbit, and immediately removed a portion of lung, liver, intestine, muscle, and a whole kidney. I rapidly washed them in 0.75 p.c. salt solution, and put them, hot as they were, at once into the well of the machine and covered them with 0.75 p.c. salt solution. I put the freezing mixture into the box and covered the whole with cotton wadding. To freeze them thoroughly required sixteen minutes. I then made sections, as fine as any one could possibly desire, of all the several tissues at once, -picked them off the knife with a camel-hair pencil, and put them into separate vessels for examination."' (178)