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Sent From (Definite): Edward NettleshipSent To (Definite): Karl PearsonDate: 11 Sep 1911
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Holder (Definite): University College London: Special Collections
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Sent from Edward Nettleship
11 Sep 1911
Description:
[re: inc. of depiction of pup of Jakc & Jill in draft]
‘About the hairs in the skin of the above puppy & in the nose-skin of (I think) two other similar specimens of alter date that I have at home, the proper thing of course will be for these hair-skin sections to be submitted to Dr Scott & you & reported on by [you], I being allowed to insert of quote from the Report in my description of the individual in the descriptive list of the pedigree. I of course know nothing about pigment & hair except wh. has come to me from or thro. you; & I don’t thing Coats pretends to any exhaustive knowledge of it. The 2 sorts, “granular” & “diffuse” I know about of course, & that the latter is to a great extent, at present, the pigment of “coloured albinism”.
In my ignorance I thought both kinds were intra-cellular; I thought of the “granular” as what, if the hair were a test-tube of fluid, would be a ppt., of the diffuse as a coloured solution.
Now you speak of inter-cellular pigment & granular pigment & I infer from the way you write that “inter-cellular” & “granular” are, for this purpose the same, i.e. that the granular (wh. for convenience I call the ppt[ed?] pigment, above) pigment is between the cells, not within them, & thus “diffuse” within them.
Scott – underlined red [i.e. in draft] – p.p. 4, 5, 8, 13, confirms the above; indeed yours is I suppose based on him largely?
You speak of occasional difficulty in deciding whether intercellular pigment is due to granules or not, & Scott (p. 4) speaks of air-bubbles wh. make the hair containing them macroscopically light (air-bubbles were I fancy a while back assigned a large share in the [graying/whitening] of senile hair!).
In a recent letter probably written just before I left home, I think I told you of (a) diffuse yellowish staining & (b)? granules or ?air-bubbles, in nose-skin of some of the puppies & that Scott or you ought to see them – add, now, to those spleens, this further one of Coats’s (really another one of the same series, & from me) & we (= you) will get the things straight in plenty of time to go into my new section. I shd. like to examine, for my own instruction my sections & to examine the additional one of Coats when I get home before sending them to you, so as to get all the good I can from them whatever revision you (& Scott?) find necessary to make.
Yrs very sincerely,
E. Nettleship.
...’
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Sent to Karl Pearson
11 Sep 1911
Description:
[re: inc. of depiction of pup of Jakc & Jill in draft]
‘About the hairs in the skin of the above puppy & in the nose-skin of (I think) two other similar specimens of alter date that I have at home, the proper thing of course will be for these hair-skin sections to be submitted to Dr Scott & you & reported on by [you], I being allowed to insert of quote from the Report in my description of the individual in the descriptive list of the pedigree. I of course know nothing about pigment & hair except wh. has come to me from or thro. you; & I don’t thing Coats pretends to any exhaustive knowledge of it. The 2 sorts, “granular” & “diffuse” I know about of course, & that the latter is to a great extent, at present, the pigment of “coloured albinism”.
In my ignorance I thought both kinds were intra-cellular; I thought of the “granular” as what, if the hair were a test-tube of fluid, would be a ppt., of the diffuse as a coloured solution.
Now you speak of inter-cellular pigment & granular pigment & I infer from the way you write that “inter-cellular” & “granular” are, for this purpose the same, i.e. that the granular (wh. for convenience I call the ppt[ed?] pigment, above) pigment is between the cells, not within them, & thus “diffuse” within them.
Scott – underlined red [i.e. in draft] – p.p. 4, 5, 8, 13, confirms the above; indeed yours is I suppose based on him largely?
You speak of occasional difficulty in deciding whether intercellular pigment is due to granules or not, & Scott (p. 4) speaks of air-bubbles wh. make the hair containing them macroscopically light (air-bubbles were I fancy a while back assigned a large share in the [graying/whitening] of senile hair!).
In a recent letter probably written just before I left home, I think I told you of (a) diffuse yellowish staining & (b)? granules or ?air-bubbles, in nose-skin of some of the puppies & that Scott or you ought to see them – add, now, to those spleens, this further one of Coats’s (really another one of the same series, & from me) & we (= you) will get the things straight in plenty of time to go into my new section. I shd. like to examine, for my own instruction my sections & to examine the additional one of Coats when I get home before sending them to you, so as to get all the good I can from them whatever revision you (& Scott?) find necessary to make.
Yrs very sincerely,
E. Nettleship.
...’